6 Best Ways To Restore Your Gut Health After an Antibiotic, from Expert Doctors

Published on Dec. 04, 2024

Antibiotics can do a number on your G.I. system. An infectious disease MD and a Cleveland Clinic gut health doctor share how to get your tummy back in balance.

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About the experts:

  • Linda Yancey, MD, is board-certified in infectious disease and internal medicine with over two decades of experience practicing in Texas. She completed her residency at Mayo Clinic in Scottsdale, Arizona, and fellowship at Baylor College of Medicine in Houston. Currently, Dr. Yancey serves as an infectious disease specialist at Memorial Hermann Hospital in Houston.
  • Gail Cresci, PhD, RD, is a gut microbiome researcher with Cleveland Clinic’s Digestive Disease Institute and Director of Nutrition Research with Cleveland Clinic’s Center for Human Nutrition.

Antibiotics are important medications designed to combat bacterial infections by killing bacteria or inhibiting their growth. They’re essential for treating conditions like strep throat, urinary tract infections, and pneumonia, among others. According to the Centers for Disease Control and Prevention (CDC), healthcare providers in the U.S. prescribed 236.4 million antibiotics in outpatient settings in 2022, which is about seven prescriptions for every 10 people. With the rise in respiratory viruses in recent years, the examination of antibiotics is perhaps even more relevant than ever.

“Antibiotics are life-saving drugs, but they do come with side effects,” says Linda Yancey, MD, an infectious disease specialist at Memorial Hermann Hospital in Houston. “The most common symptom people will experience after antibiotics is diarrhea. This can sometimes be very severe.”

To Dr. Yancey’s point: It’s important to understand that, while antibiotics eliminate harmful bacteria, they can also impact the beneficial bacteria in your gut microbiome. This community of “good” bacteria plays an important role in digestion, nutrient absorption, immune system function, and even mood regulation. When this balance is disrupted, it can lead to problems.

Common signs of an unhealthy gut after antibiotic use can include gastrointestinal symptoms like diarrhea, bloating, gas, abdominal pain, or constipation.

How long does it take for gut bacteria to recover after antibiotics?

“Studies show it can take up to 14 to 30 days for the gut microbiota to restore following antibiotic usage,” says Gail Cresci, PhD, RD, a gut microbiome researcher with the Cleveland Clinic’s Digestive Disease Institute. In some individuals, the disruption in microbiome composition may be longer, potentially extending for months.

To put this in perspective, Dr. Yancey suggests thinking of the gut like a forest. When a forest fire sweeps through, it takes time for the vegetation to regrow and for wildlife to return. “In the same way, it takes time for the gut flora to regrow,” she says.

Given how essential a balanced gut microbiome is to overall health, it’s natural to seek ways to help restore it after antibiotic use. Ahead, Dr. Yancey and Dr. Cresci share ways to restore gut health after antibiotics.

6 ways to restore gut health after antibiotics

6 Ways To Restore Gut Health After An Antibiotic
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1. Eat a diet rich in fiber

One of the best ways to restore gut health after antibiotics is by consuming plenty of fiber, “particularly prebiotic soluble fermentable fibers from fruits, vegetables, and complex carbohydrates,” Dr. Cresci says.

Prebiotic soluble fermentable fibers are types of dietary fiber that feed the beneficial bacteria in your gut. They dissolve in water and are fermented by gut microbes. Examples include inulin found in garlic, onions, and bananas; pectins from apples and citrus fruits; and beta-glucans in oats and barley.

It’s also important to avoid processed foods, such as white bread, sugary cereals, chips, and fast food, which can disrupt the balance of good bacteria in your gut. These foods are often low in fiber and high in unhealthy fats and sugars that can negatively affect gut health.

6 Ways To Restore Gut Health After An Antibiotic
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2. Consume fermented foods

To help restore gut health after antibiotics, Dr. Cresci recommends adding fermented foods that contain live cultures—such as kombucha, yogurt, kefir, and kimchi—to your meals. Consuming fermented foods introduces helpful microbes back into your digestive system, promoting a balanced gut flora essential for proper digestion, nutrient absorption, and a strong immune system.

6 Ways To Restore Gut Health After An Antibiotic
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3. Consider taking supplements

In addition to dietary changes, you might consider taking prebiotic and probiotic supplements to support your gut health. Probiotics introduce beneficial bacteria into your digestive system, while prebiotics provide the essential nutrients that these bacteria need to thrive.

However, Dr. Yancey emphasizes that there is no over-the-counter solution to quickly restore your gut flora, as supplements alone cannot achieve this. Instead, she recommends prioritizing a balanced diet rich in a variety of fruits, vegetables, nuts, lean meats, and dairy products to naturally support gut health.

If you do decide to take supplements, be sure to consult with your healthcare provider to choose the best options for your needs.

6 Ways To Restore Gut Health After An Antibiotic
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5. Get enough sleep

A good night’s sleep is essential for overall health and becomes even more important after taking antibiotics. If you’ve been ill, your sleep quality might have been affected.

Dr. Cresci emphasizes that ensuring you get enough rest is key to restoring gut health. Experts recommend getting seven to nine hours of sleep each night to support your body’s recovery.

6 Ways To Restore Gut Health After An Antibiotic
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6. Exercise

Regular physical activity is a powerful tool for restoring gut health after antibiotics. Research, such as one 2017 paper by scientists in Italy, has suggested that exercise promotes the growth of beneficial bacteria and increases the diversity of your gut microbiome, which is important to overall digestive health. Exercise also improves blood flow to the gut and reduces inflammation, creating an environment where healthy bacteria can thrive.

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What is the best probiotic after antibiotics?

Says Dr. Cresci: “There are a few probiotic strains that have been studied and shown to be beneficial for antibiotic-associated diarrhea.” These include Lactobacillus rhamnosus GG (LGG), Saccharomyces boulardii, and Bifidobacterium animalis spp. lactis (BB12).

You can find these strains in many high-quality probiotic supplements and certain fortified foods, such as yogurt or kefir. Always make sure you check product labels to verify expiration date and confirm it contains live and active cultures.

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